Hi Bernie, actually time plays 3rd priority position to how you get customers to open your email. #1 is the message - what are you saying to get them to open the email?- on the subject line. #2 is making sure the content gives your customer information and opportunities that engage them into action. #3 is the day or time of day. Then as some have mentioned.. TEST! Be prepared to try different messages and times to see what resonates with your audience. Make sure to choose a service...

Finding the right online marketing tools can seem like a difficult task. Luckily, the best email platforms offer an unlimited number of messages and progressive pricing packages. This means that your bills depend on the number of subscribers. So, if you are a small business with a few hundred mailing list subscribers, you will only have to pay a small monthly rate. Constant Contact offers great price points for small businesses. You can even find an email platform that offers free plans for those who need only a limited number of features, like Benchmark. If you are unsure what your needs are, you can opt for a pay-as-you-go plan.
Moonmail is great platform that utilizes Amazon SES  – which means you are only paying for what you send (vs. subscribers in your account), making it at cost effective solution for small businesses. With a powerful drag and drop editor, deep analytics, and built-in heatmaps (so you can see what content is working) all under a clean and easy-to-use interface, it’s a excellent choice to scale your email marketing needs.
Obviously, it takes more work to create and place guest posts, but it’s worth it if the publication is aligned and authoritative. We found a way to create additional value with this as well by working with internal HubSpot experts who wanted to get their thoughts out on a given subject. For example, here’s a guest post that Blake Toder wrote for the Usabilla blog:

Robly's OpenGen technology utilizes a traditional email campaign process; however, OpenGen then resends your campaign one to 10 days later, with a different subject line to those subscribers who didn't open the first campaign. The system sends emails one at a time, at the moment subscribers are most likely to check their inboxes. The service features A/B testing, a pop-up widget to increase contacts and mobile-responsive templates.
But your service provider isn't your only worry. If you've opted for any third-party email integration, like combining your email with a third-party customer relationship management (CRM) provider (such as Salesforce), that opens your company's email up to either data-snooping apps deployed by Salesforce or to any data breaches that originate with that service. So the more informed you can be about what's attached to your email service, how that data's being used and accessed and especially by whom, the better off you'll be when it comes time to send confidential email.
Nearly all free email services have inbox ads, so there’s that most services include. Since they’re all but unavoidable, look for services that make them less obtrusive. Some place ads to the side, so they don’t create too much distraction. However, some services place ads all around the inbox, making it difficult to navigate the program. Some free email services even allow pop-up ads that cover your inbox and require you to click out of them to access your messages.
WhatCounts, which recently joined forces with Windsor Circle, offers email marketing software can be operated from the cloud or on your own servers. Features include a life cycle workflow builder, behavioral personalization, advanced segmentation, dynamic content, a relational database, responsive templates, campaign analytics, A/B testing and social sharing.
Email marketing is a cheap and effective way to reach your customers, build a community and increase sales. The best email marketing software allows you to send professional emails with little design experience. It also enables you to create custom, automated email journeys, and help you create extensive customer lists with segmentation capabilities.
“Third, tell me how it benefits me. I’m very very active in my charity work, but your startup is not a charity…”We thought you’d enjoy meeting young entrepreneurs” – bzzzzt. I DO enjoy meeting young entrepreneurs, I do it all the time as a matter of routine at conferences and through friends and so on. But if you’d like more than a friendly pat on the back and encouragement, then treat me like a businessperson – let’s find something that’s mutually agreeable. “If you could join us as an advisor, we’d be able to compensate you with stock options in a quantity appropriate to our stage of development.” – yay.”

dotmailer is a marketing automation platform that empowers B2B, B2C and e-commerce businesses. The software enables marketers in 150 countries to use advanced data to design, test and send powerful automated campaigns. In addition to being a Magento Premier Technology Partner, dotmailer integrates seamlessly with other ecommerce platforms and CRMs.
That is why you need to carefully check the reputation of the vendor(s) and constantly track each campaign. ClickMeter provides you with relevant tools to manage and track solo ads campaigns: real-time and reliable tracking, advanced redirection options (including affiliate link cloaking), destination URL monitoring and click-fraud detection. More info here: https://clickmeter.xyz/track-solo-ads

Things are probably more complicated than that, though. As a recent survey conducted by market research firm Statista clearly shows, email is one of the most popular apps for mobile devices across most organizations and even consumers. Given how many workflows, business processes, and just plain important communications take place over email, this is one area where you likely shouldn't skimp.
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